Bilateral trade for 2009 was US$4.6 billion, with the US surplus with Panama totaling US$4 billion.

The US is Panama’s largest trading partner, accounting for 35% of its exports and 33% of its imports.

Fifteen percent of all US trade passes through the Panama Canal each year. 70% of all cargo and 56% of all vessels transiting the Canal have a US origin or destination.

Panama is a major destination for US foreign investment, attracting more foreign direct investment than all other Central American nations combined. The stock of US FDI in Panama totals roughly $25 billion.